Partridge, K,, Johannessen, A.J., Tauler, A., Pryme, I.F. and Hesketh, J.E. (1999). Competition between the signal sequence and a 3`UTR localisation signal during redirection of beta-globin mRNA to endoplasmic reticulum: implications for biotechnology. Cytotechnology 30: 37-47- Corporate profile: UniTargetingResearch enhances protein production.
Genetic Engineering News, 2004, Vol. 24, No. 2.
- Stern, B. and Pryme, I.F. (2005). Improved protein production from mammalian cells.
BIOforum Europe 6: 38-40.
- Knappskog, S., Ravneberg, H., Gjerdrum, C., Τröβe, C., Stern, B. and Pryme, I.F.
(2007). The level of synthesis and secretion of Gaussia princeps luciferase in transfected CHO cells is heavily dependent on the choice of signal peptide.
J. Biotechnol. 128: 705-715.
- Stern, B., Gjerdrum, C., Knappskog, S., Minsaas, L., Nyland, S., Olsen, L.C., Olsen, L., Oveland, E., Ravneberg, H., Tröße, C., Tveit, A., Vollsund, E., Hesketh, J.E., Tauler, A. and Pryme I.F. (2007). UTRtechTM : Exploiting mRNA targeting to increase protein secretion from mammalian cells, In: Cell Technology for Cell Products, R. Smith ed., (Springer, Dordrecht, The Netherlands), pp. 261-268.
- Stern, B., Olsen, L.C., Tröße, C., Ravneberg, H. and Pryme, I.F. (2007). Improving mammalian cell factories : The selection of signal peptide has a major impact on recombinant protein synthesis and secretion in mammalian cells.?Trends Cell Mol. Biol. 2: 1-17.
- Τröβe, C., Ravneberg, H., Stern, B. and Pryme, I.F. (2007). Vectors encoding seven oikosin signal peptides transfected into CHO cells differ greatly in mediating Gaussia luciferase and human endostatin production although mRNA levels are largely unaffected.
Gene Regulation and Systems Biology 1: 303-312.
- Reisinger, H., Steinfellner, W., Stern, B., Katinger, H. & Kunert, R. (2008). The absence of effect of gene copy number and mRNA level on the amount of mAb secretion from mammalian cells. Appl. Microbiol. Biotechnol. 81: 701-710.
- Optun, A., Ravneberg, H., Pryme, I.F. and Stern, B., Single amino acid mutations in the Oikosin 1 signal peptide can exert either positive or negative effects on the production of a recombinant protein in transfected CHO cells. To be submitted
